Association between serum levels of Adipokines and Polycystic Ovary Syndrome

Authors

  • Adeleh Razavi
  • Fatemeh Hashemi
  • Maryam Emadi
  • Mehdi Hedayati
  • Naghmeh Saadati
  • Sepideh Haghighi
Abstract:

  Polycystic ovary syndrome (PCOS) is the most common endocrine disorder associated with metabolic disorders and infertility. Evidence suggests that the adipose tissue secreted products, adipokines, play an important role in the pathophysiology of PCOS. Reciprocally, PCOS influences on the adipokines serum content, also on gene or protein expression of some of them. Finding out of association between serum levels of adipokines and PCOS will help to understand the pathology of PCOS and identify treatment solutions of this syndrome. In this paper, we review the assosiation of several known adipokines with polycystic ovary syndrome. Correspondence: Mehdi. Hedayati, PhD. Cellular and Molecular Research Center, Shahid Beheshti University of Medical Sciences. Tehran, Iran. Tel:+98 21 22432498 Email: [email protected]

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Association between Follicular Fluid Leptin and Serum Insulin Levels in Nonoverweight Women with Polycystic Ovary Syndrome

AIMS We evaluated the links between leptin and visfatin levels and fertilization rates in nonoverweight (NOW) women with PCOS (NOW-PCOS) from Apulia undergoing in vitro fertilization/embryo transfer (IVF). MATERIALS AND METHODOLOGY We recruited 16 NOW women with PCOS (NOW-PCOS) and 10 normally ovulating NOW women (control-NOW). All women underwent IVF. Androgens, 17- β -estradiol (17 β -E2), ...

full text

Relationship between Serum Levels of Anti-Mullerian Hormone, Adiponectin and Oxidative Stress Markers in Patients with Polycystic Ovary Syndrome

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Anti-Mullerian hormone (AMH) is a valid indicator of ovarian function and is used for PCOS diagnosis. Some studies have shown that adipokines affect the synthesis of AMH, and therefore they are somehow related in function. The aim of the present study was to determine the relationshi...

full text

Increased serum neopterin levels in women with polycystic ovary syndrome.

Polycystic ovary syndrome (PCOS) occurs in 5-10% of premenopausal women. Studies suggest that PCOS is associated with increased risk of coronary heart disease (CHD). To investigate this relationship, 15 PCOS women (group 1) and 10 healthy women (group 2) were studied. Blood leukocyte counts (white blood cells, WBC) and serum levels of total cholesterol, HDL-cholesterol, LDL-cholesterol, sensiti...

full text

Serum adiponectin levels in women with polycystic ovary syndrome.

BACKGROUND Adiponectin is regarded as a possible link between adiposity and insulin resistance. The study aim was to measure serum adiponectin levels in women with polycystic ovary syndrome (PCOS) and to assess possible correlations between adiponectin and the hormonal or metabolic parameters of the syndrome. METHODS Eighty-five selected women were classified as: Group I (n = 35) with PCOS + ...

full text

Relationship between serum cystatin C and polycystic ovary syndrome

BACKGROUND Polycystic ovary syndrome (PCOS) causes an increased risk of metabolic cardiovascular syndrome. Also, cystatin C serum levels are associated with the risk of cardiovascular events in metabolic syndrome patients. OBJECTIVE To investigate the relationship between cystatin C in PCOS patients. MATERIALS AND METHODS 35 women with PCOS were compared to 35 women with healthy matched age...

full text

The relationship between Polycystic ovary syndrome and vitamin D levels

OBJECTIVE The main aim of this study was to determine the association of serum 25-hydroxyvitamin D (25-OH D) levels with hormonal, clinical and metabolic profile in patients with and without Polycystic ovary syndrome (PCOS). MATERIALS AND METHODS Forty-eight normal-weight (body mass index (BMI) of 19-24.99 kg/m2) women with PCOS, 36 overweight (BMI of 25-29.9 kg/m2) women with PCOS and 56 nor...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 19  issue None

pages  389- 397

publication date 2015-12

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023